Antisense Oligonucleotide Extraction Optimization Reveals Significant Differences Between Non-Human Primate Spinal Cord, Mouse Spinal Cord, and Mouse Brain Tissue Homogenates
Discover the critical differences in antisense oligonucleotide (ASO) extraction methods across non-human primate spinal cord, mouse spinal cord, and mouse brain tissues. Our research highlights how unique tissue properties demand distinct extraction techniques for optimal results.
Download our poster to learn more.
Oligonucleotides: Where we started, where we stand, and where we would like to go
Oligonucleotides, which are short chains of nucleotides that make up DNA and RNA, are used in a wide range of applications in bioanalysis and play a critical role in understanding the molecular mechanisms of living cells and diseases.
Organic Synthetic Chemist, Troy Voelker PhD, discusses common methods to support the bioanalysis of oligonucleotides (OGNTs) and a future perspective regarding areas for improvement.
His insights explores a range of analytical techniques for OGNTs, including:
-Basics of oligonucleotide bioanalysis
-Selecting an approach
-Methods of extraction
-Handling Hybridization methods
-Goals for future analysis
Discover how future predictions for oligonucleotide bioanalysis will help improve medicine, therapeutics and genetic testing.