In Situ Hybridization
RNAscope is an advanced RNA in situ hybridization (ISH) technology that allows for the precise detection, localization, and quantification of RNA molecules within tissue and cell samples. Compared to traditional ISH methods, RNAscope offers higher sensitivity, specificity, and multiplexing capabilities, making it an essential tool in biomarker discovery, disease pathology, and therapeutic development.
Unlike conventional techniques, which often struggle with low transcript detection and high background noise, RNAscope’s proprietary double Z-probe technology ensures precise target recognition with minimal off-target effects. This technology enables high-resolution spatial mapping of RNA biomarkers while maintaining tissue integrity, making it ideal for FFPE, fresh frozen, and cell-based assays.
