Islet Amyloid Polypeptide (IAPP) is a peptide hormone produced by the pancreas’ beta cells that regulates blood glucose. Research on IAPP and its role in diabetes is ongoing, and there is a need for a reliable method to accurately detect this hormone at clinically relevant levels and possibly the different forms of the peptide. We set out to validate a hybrid LCMS assay for this biomarker that could be validated to an appropriate level to support clinical studies.

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