The significance of oligonucleotides (OGNTs) in drug development is increasing rapidly, as they offer promising and life-changing treatments that can improve patients’ lives. However, the promising and vast opportunities of OGNTs come with a unique set of challenges and nuances unlike other types of molecules.
Within bioanalysis, there are 5 main approaches for OGNTs to consider:
- LC/UV
- LC/MS/MS
- Hybridization LF/FD
- LC/HRMS
- Hybridization ELISA
Learn how to evaluate the pros and cons of each approach to decide what’s best for your OGNTs.