As cancer advances, tumor cells come into contact with new cell types within the microenvironment, but it is still unclear how the tumor cells adapt to new environments. Spatial transcriptomics is a powerful approach to uncover mechanisms that allow tumors to invade the microenvironment and help discover biomarkers for potential therapeutic targets.
In this application note, we outline how we fine-tuned and merged spatial transcriptomics with laser microdissection (LMD) to identify distinct patterns in genes in tumor cells throughout the stages of cancer progression.
Download our application note to learn more: